Gene basic information
LiverAtlas Gene ID |
HuLG005015 |
Entrez Gene ID |
|
Official Gene Symbol |
TYMS |
Synonyms |
HST422|MGC88736|TMS|TS |
Gene name |
thymidylate synthetase |
Gene Type |
protein-coding |
Chromosome |
18 |
Genomics Location |
18p11.32 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:12441
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000082 |
G1/S transition of mitotic cell cycle |
GO:0000083 |
regulation of transcription involved in G1/S phase of mitotic cell cycle |
GO:0000166 |
nucleotide binding |
GO:0000278 |
mitotic cell cycle |
GO:0004799 |
thymidylate synthase activity |
GO:0005542 |
folic acid binding |
GO:0005625 |
soluble fraction |
GO:0005829 |
cytosol |
GO:0006139 |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
GO:0006206 |
pyrimidine base metabolic process |
GO:0006231 |
dTMP biosynthetic process |
GO:0006260 |
DNA replication |
GO:0006281 |
DNA repair |
GO:0007568 |
aging |
GO:0008168 |
methyltransferase activity |
GO:0009157 |
deoxyribonucleoside monophosphate biosynthetic process |
GO:0009165 |
nucleotide biosynthetic process |
GO:0016740 |
transferase activity |
GO:0019088 |
immortalization of host cell by virus |
GO:0031100 |
organ regeneration |
GO:0042493 |
response to drug |
GO:0046078 |
dUMP metabolic process |
GO:0046134 |
pyrimidine nucleoside biosynthetic process |
GO:0046683 |
response to organophosphorus |
GO:0048015 |
phosphatidylinositol-mediated signaling |
GO:0048037 |
cofactor binding |
GO:0048589 |
developmental growth |
GO:0051216 |
cartilage development |
GO:0051384 |
response to glucocorticoid stimulus |
GO:0055086 |
nucleobase, nucleoside and nucleotide metabolic process |
GO:0060574 |
intestinal epithelial cell maturation |