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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005022

Entrez Gene ID

7314

Official Gene Symbol

UBB

Synonyms

FLJ25987|MGC8385|RPS27A|UBA52|UBC

Gene name

ubiquitin B

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p12-p11.2

Known cancer genes

Yes

Protein products

Ubiquitin B

Polyubiquitin-B

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12463
MIM:191339
Ensembl:ENSG00000170315
HPRD:06771
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000084

S phase of mitotic cell cycle

GO:0000187

activation of MAPK activity

GO:0000216

M/G1 transition of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006281

DNA repair

GO:0006915

apoptosis

GO:0006916

anti-apoptosis

GO:0006977

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0007249

I-kappaB kinase/NF-kappaB cascade

GO:0007254

JNK cascade

GO:0008063

Toll signaling pathway

GO:0008624

induction of apoptosis by extracellular signals

GO:0010008

endosome membrane

GO:0016032

viral reproduction

GO:0016044

cellular membrane organization

GO:0016070

RNA metabolic process

GO:0016071

mRNA metabolic process

GO:0016197

endosome transport

GO:0030666

endocytic vesicle membrane

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0032480

negative regulation of type I interferon production

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

GO:0042981

regulation of apoptosis

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0045087

innate immune response

GO:0048011

nerve growth factor receptor signaling pathway

GO:0050852

T cell receptor signaling pathway

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO:0051403

stress-activated MAPK cascade

GO:0051436

negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051437

positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051439

regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle