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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005027

Entrez Gene ID

7319

Official Gene Symbol

UBE2A

Synonyms

HHR6A|RAD6A|UBC2

Gene name

ubiquitin-conjugating enzyme E2A

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xq24

Known cancer genes

Yes

Protein products

Ubiquitin carrier protein

Ubiquitin-conjugating enzyme E2A (RAD6 homolog), isoform CRA a

Ubiquitin-conjugating enzyme E2 A

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12472
MIM:312180
Ensembl:ENSG00000077721
HPRD:02422
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000785

chromatin

GO:0000790

nuclear chromatin

GO:0001701

in utero embryonic development

GO:0001741

XY body

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0006281

DNA repair

GO:0006301

postreplication repair

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0008284

positive regulation of cell proliferation

GO:0009411

response to UV

GO:0016568

chromatin modification

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0031625

ubiquitin protein ligase binding

GO:0033522

histone H2A ubiquitination

GO:0051865

protein autoubiquitination

GO:0060135

maternal process involved in female pregnancy

GO:0070936

protein K48-linked ubiquitination

GO:0070979

protein K11-linked ubiquitination