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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005029

Entrez Gene ID

7321

Official Gene Symbol

UBE2D1

Synonyms

E2(17)KB1|SFT|UBC4/5|UBCH5|UBCH5A

Gene name

ubiquitin-conjugating enzyme E2D 1

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q21.1

Known cancer genes

Yes

Protein products

Ubiquitin-conjugating enzyme E2 D1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12474
MIM:602961
Ensembl:ENSG00000072401
HPRD:04267
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000166

nucleotide binding

GO:0000209

protein polyubiquitination

GO:0000278

mitotic cell cycle

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0007094

mitotic cell cycle spindle assembly checkpoint

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0030509

BMP signaling pathway

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0031398

positive regulation of protein ubiquitination

GO:0051436

negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051437

positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051439

regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0070936

protein K48-linked ubiquitination