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Gene basic information

LiverAtlas Gene ID

HuLG005032

Entrez Gene ID

7324

Official Gene Symbol

UBE2E1

Synonyms

UBCH6

Gene name

ubiquitin-conjugating enzyme E2E 1

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p24.2

Known cancer genes

Yes

Protein products

Ubiquitin carrier protein

Ubiquitin carrier protein

Ubiquitin-conjugating enzyme E2 E1

Database cross reference

HGNC:12477
MIM:602916
Ensembl:ENSG00000170142
HPRD:04225
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000151

ubiquitin ligase complex

GO:0000166

nucleotide binding

GO:0000209

protein polyubiquitination

GO:0000278

mitotic cell cycle

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005829

cytosol

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0007094

mitotic cell cycle spindle assembly checkpoint

GO:0010390

histone monoubiquitination

GO:0016567

protein ubiquitination

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0032020

ISG15-protein conjugation

GO:0033523

histone H2B ubiquitination

GO:0042296

ISG15 ligase activity

GO:0051436

negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051437

positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051439

regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0070936

protein K48-linked ubiquitination