HuLG005068

Entrez Gene ID

7372

Official Gene Symbol

UMPS

Synonyms

OPRT

Gene name

uridine monophosphate synthetase

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q13

Known cancer genes

Yes

Protein products

Uridine monophosphate synthetase (Orotate phosphoribosyl transferase and orotidine-5'-decarboxylase), isoform CRA b

Orotidine 5'-phosphate decarboxylase

Uridine monophosphate synthetase isoform E

Uridine monophosphate synthetase isoform I

Uridine 5'-monophosphate synthase

Uridine 5'-monophosphate synthase

Database cross reference

HGNC:12563
MIM:613891
Ensembl:ENSG00000114491
HPRD:02022
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

GO annotation

GO:0004588

orotate phosphoribosyltransferase activity

GO:0004590

orotidine-5'-phosphate decarboxylase activity

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006206

pyrimidine base metabolic process

GO:0006207

de novo' pyrimidine base biosynthetic process

GO:0006221

pyrimidine nucleotide biosynthetic process

GO:0006222

UMP biosynthetic process

GO:0009116

nucleoside metabolic process

GO:0016757

transferase activity, transferring glycosyl groups

GO:0016829

lyase activity

GO:0044205

de novo' UMP biosynthetic process

GO:0046134

pyrimidine nucleoside biosynthetic process

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process