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Gene basic information

LiverAtlas Gene ID

HuLG005097

Entrez Gene ID

7414

Official Gene Symbol

VCL

Synonyms

CMD1W|CMH15|MVCL

Gene name

vinculin

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q22.2

Known cancer genes

Yes

Protein products

cDNA FLJ45031 fis, clone BRAWH3018548, highly similar to Vinculin

Vinculin

Vinculin

Database cross reference

HGNC:12665
MIM:193065
Ensembl:ENSG00000035403
HPRD:01900
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

 

Ontology annotation

GO ID

GO annotation

GO:0001725

stress fiber

GO:0002009

morphogenesis of an epithelium

GO:0002166

beta-dystroglycan binding

GO:0002576

platelet degranulation

GO:0003779

actin binding

GO:0005198

structural molecule activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005884

actin filament

GO:0005886

plasma membrane

GO:0005911

cell-cell junction

GO:0005912

adherens junction

GO:0005913

cell-cell adherens junction

GO:0005916

fascia adherens

GO:0005925

focal adhesion

GO:0006928

cellular component movement

GO:0006936

muscle contraction

GO:0007155

cell adhesion

GO:0007160

cell-matrix adhesion

GO:0007596

blood coagulation

GO:0008013

beta-catenin binding

GO:0017048

Rho GTPase binding

GO:0030032

lamellipodium assembly

GO:0030055

cell-substrate junction

GO:0030168

platelet activation

GO:0030336

negative regulation of cell migration

GO:0034333

adherens junction assembly

GO:0034394

protein localization at cell surface

GO:0043034

costamere

GO:0043234

protein complex

GO:0043297

apical junction assembly

GO:0045294

alpha-catenin binding

GO:0045296

cadherin binding

GO:0090136

epithelial cell-cell adhesion