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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005098

Entrez Gene ID

7415

Official Gene Symbol

VCP

Synonyms

IBMPFD|MGC131997|MGC148092|MGC8560|TERA|p97

Gene name

valosin containing protein

Gene Type

protein-coding

Chromosome

9

Genomics Location

9p13.3

Known cancer genes

Yes

Protein products

VCP protein

VCP protein

Valosin-containing protein

Valosin-containing protein

Transitional endoplasmic reticulum ATPase

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:12666
MIM:601023
Ensembl:ENSG00000165280
HPRD:03013
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000502

proteasome complex

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005783

endoplasmic reticulum

GO:0005792

microsome

GO:0005829

cytosol

GO:0006200

ATP catabolic process

GO:0006281

DNA repair

GO:0006302

double-strand break repair

GO:0006810

transport

GO:0006888

ER to Golgi vesicle-mediated transport

GO:0006919

activation of caspase activity

GO:0006974

response to DNA damage stimulus

GO:0008289

lipid binding

GO:0016567

protein ubiquitination

GO:0016787

hydrolase activity

GO:0016887

ATPase activity

GO:0019903

protein phosphatase binding

GO:0019904

protein domain specific binding

GO:0030433

ER-associated protein catabolic process

GO:0030968

endoplasmic reticulum unfolded protein response

GO:0030970

retrograde protein transport, ER to cytosol

GO:0031593

polyubiquitin binding

GO:0032403

protein complex binding

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

GO:0042802

identical protein binding

GO:0042981

regulation of apoptosis

GO:0043161

proteasomal ubiquitin-dependent protein catabolic process

GO:0045184

establishment of protein localization

GO:0045732

positive regulation of protein catabolic process

GO:0051260

protein homooligomerization

GO:0070842

aggresome assembly