Gene basic information
| LiverAtlas Gene ID |
HuLG005107 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
VHL |
|
Synonyms |
HRCA1|RCA1|VHL1 |
|
Gene name |
von Hippel-Lindau tumor suppressor |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p25.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:12687
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0000902 |
cell morphogenesis |
|
GO:0001525 |
angiogenesis |
|
GO:0001666 |
response to hypoxia |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005829 |
cytosol |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006508 |
proteolysis |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006950 |
response to stress |
|
GO:0008134 |
transcription factor binding |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0016020 |
membrane |
|
GO:0016567 |
protein ubiquitination |
|
GO:0030163 |
protein catabolic process |
|
GO:0030182 |
neuron differentiation |
|
GO:0030198 |
extracellular matrix organization |
|
GO:0030891 |
VCB complex |
|
GO:0042069 |
regulation of catecholamine metabolic process |
|
GO:0043534 |
blood vessel endothelial cell migration |
|
GO:0045471 |
response to ethanol |
|
GO:0045597 |
positive regulation of cell differentiation |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0050821 |
protein stabilization |
|
GO:0051291 |
protein heterooligomerization |
