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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005121

Entrez Gene ID

7448

Official Gene Symbol

VTN

Synonyms

V75|VN|VNT

Gene name

vitronectin

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q11

Known cancer genes

Yes

Protein products

Vitronectin

Vitronectin

Related liver disease name

Liver fibrosis and liver cirrhosis

Chronic hepatitis

Hepatocellular carcinoma

Alcoholic liver disease

Database cross reference

HGNC:12724
MIM:193190
Ensembl:ENSG00000255604
HPRD:01902
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005044

scavenger receptor activity

GO:0005178

integrin binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0006955

immune response

GO:0007155

cell adhesion

GO:0007160

cell-matrix adhesion

GO:0008201

heparin binding

GO:0010811

positive regulation of cell-substrate adhesion

GO:0010951

negative regulation of endopeptidase activity

GO:0014911

positive regulation of smooth muscle cell migration

GO:0030195

negative regulation of blood coagulation

GO:0030198

extracellular matrix organization

GO:0030247

polysaccharide binding

GO:0030949

positive regulation of vascular endothelial growth factor receptor signaling pathway

GO:0031012

extracellular matrix

GO:0032092

positive regulation of protein binding

GO:0033627

cell adhesion mediated by integrin

GO:0048260

positive regulation of receptor-mediated endocytosis

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

GO:0050840

extracellular matrix binding

GO:0061302

smooth muscle cell-matrix adhesion

GO:0071062

alphav-beta3 integrin-vitronectin complex

GO:0090303

positive regulation of wound healing