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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005143

Entrez Gene ID

7481

Official Gene Symbol

WNT11

Synonyms

HWNT11|MGC141946|MGC141948

Gene name

wingless-type MMTV integration site family, member 11

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13.5

Known cancer genes

Yes

Protein products

Protein Wnt-11

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12776
MIM:603699
Ensembl:ENSG00000085741
HPRD:04741
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001649

osteoblast differentiation

GO:0001664

G-protein-coupled receptor binding

GO:0001934

positive regulation of protein phosphorylation

GO:0003151

outflow tract morphogenesis

GO:0005099

Ras GTPase activator activity

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006468

protein phosphorylation

GO:0007165

signal transduction

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

GO:0007275

multicellular organismal development

GO:0007492

endoderm development

GO:0009798

axis specification

GO:0009952

anterior/posterior pattern formation

GO:0010628

positive regulation of gene expression

GO:0030182

neuron differentiation

GO:0030282

bone mineralization

GO:0030295

protein kinase activator activity

GO:0030308

negative regulation of cell growth

GO:0030325

adrenal gland development

GO:0030335

positive regulation of cell migration

GO:0030336

negative regulation of cell migration

GO:0032320

positive regulation of Ras GTPase activity

GO:0032915

positive regulation of transforming growth factor-beta2 production

GO:0034394

protein localization at cell surface

GO:0043065

positive regulation of apoptosis

GO:0043066

negative regulation of apoptosis

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0048706

embryonic skeletal system development

GO:0048844

artery morphogenesis

GO:0051496

positive regulation of stress fiber assembly

GO:0060021

palate development

GO:0060197

cloacal septation

GO:0060412

ventricular septum morphogenesis

GO:0060484

lung-associated mesenchyme development

GO:0060548

negative regulation of cell death

GO:0060675

ureteric bud morphogenesis

GO:0061037

negative regulation of cartilage development

GO:0061101

neuroendocrine cell differentiation

GO:0070830

tight junction assembly

GO:0071300

cellular response to retinoic acid

GO:0072177

mesonephric duct development

GO:0072201

negative regulation of mesenchymal cell proliferation

GO:0090037

positive regulation of protein kinase C signaling cascade

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway

GO:0090272

negative regulation of fibroblast growth factor production