HuLG005151

Entrez Gene ID

7498

Official Gene Symbol

XDH

Synonyms

XO|XOR

Gene name

xanthine dehydrogenase

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p23.1

Known cancer genes

Yes

Protein products

Putative uncharacterized protein XDH

Xanthine dehydrogenase/oxidase

Related liver disease name

Liver fibrosis and liver cirrhosis

Chronic hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:12805
MIM:607633
Ensembl:ENSG00000158125
HPRD:06363
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

GO annotation

GO:0004854

xanthine dehydrogenase activity

GO:0004855

xanthine oxidase activity

GO:0005488

binding

GO:0005506

iron ion binding

GO:0005576

extracellular region

GO:0005737

cytoplasm

GO:0005777

peroxisome

GO:0005829

cytosol

GO:0006144

purine base metabolic process

GO:0006195

purine nucleotide catabolic process

GO:0007595

lactation

GO:0009055

electron carrier activity

GO:0009115

xanthine catabolic process

GO:0016491

oxidoreductase activity

GO:0030856

regulation of epithelial cell differentiation

GO:0042803

protein homodimerization activity

GO:0043546

molybdopterin cofactor binding

GO:0046872

metal ion binding

GO:0050660

flavin adenine dinucleotide binding

GO:0051537

2 iron, 2 sulfur cluster binding

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process