Gene basic information
| LiverAtlas Gene ID |
HuLG005164 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
XRCC5 |
|
Synonyms |
FLJ39089|KARPN1|KARP1|KU80|KUB2|Ku86|NFIV |
|
Gene name |
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q35 |
|
Known cancer genes |
Yes |
|
Protein products |
Ku86 autoantigen related protein 1 Putative uncharacterized protein XRCC5 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:12833
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000723 |
telomere maintenance |
|
GO:0000783 |
nuclear telomere cap complex |
|
GO:0000784 |
nuclear chromosome, telomeric region |
|
GO:0003677 |
DNA binding |
|
GO:0003690 |
double-stranded DNA binding |
|
GO:0003691 |
double-stranded telomeric DNA binding |
|
GO:0004003 |
ATP-dependent DNA helicase activity |
|
GO:0004386 |
helicase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005694 |
chromosome |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0006281 |
DNA repair |
|
GO:0006302 |
double-strand break repair |
|
GO:0006303 |
double-strand break repair via nonhomologous end joining |
|
GO:0006310 |
DNA recombination |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0008283 |
cell proliferation |
|
GO:0016032 |
viral reproduction |
|
GO:0016817 |
hydrolase activity, acting on acid anhydrides |
|
GO:0019047 |
provirus integration |
|
GO:0019059 |
initiation of viral infection |
|
GO:0042162 |
telomeric DNA binding |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043564 |
Ku70:Ku80 complex |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0050769 |
positive regulation of neurogenesis |
|
GO:0051575 |
5'-deoxyribose-5-phosphate lyase activity |
|
GO:0060218 |
hemopoietic stem cell differentiation |
|
GO:0070419 |
nonhomologous end joining complex |
