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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005167

Entrez Gene ID

7529

Official Gene Symbol

YWHAB

Synonyms

GW128|HS1|KCIPN1|YWHAA

Gene name

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13.1

Known cancer genes

Yes

Protein products

14-3-3 protein beta/alpha

14-3-3 protein beta/alpha

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12849
MIM:601289
Ensembl:ENSG00000166913
HPRD:03184
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000165

MAPKKK cascade

GO:0000186

activation of MAPKK activity

GO:0003714

transcription corepressor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005813

centrosome

GO:0005829

cytosol

GO:0006605

protein targeting

GO:0006915

apoptosis

GO:0007173

epidermal growth factor receptor signaling pathway

GO:0007264

small GTPase mediated signal transduction

GO:0007265

Ras protein signal transduction

GO:0007411

axon guidance

GO:0008022

protein C-terminus binding

GO:0008286

insulin receptor signaling pathway

GO:0008629

induction of apoptosis by intracellular signals

GO:0008633

activation of pro-apoptotic gene products

GO:0016070

RNA metabolic process

GO:0016071

mRNA metabolic process

GO:0017053

transcriptional repressor complex

GO:0019899

enzyme binding

GO:0019904

protein domain specific binding

GO:0032403

protein complex binding

GO:0035308

negative regulation of protein dephosphorylation

GO:0042470

melanosome

GO:0042826

histone deacetylase binding

GO:0043085

positive regulation of catalytic activity

GO:0048011

nerve growth factor receptor signaling pathway

GO:0048471

perinuclear region of cytoplasm

GO:0050815

phosphoserine binding

GO:0051219

phosphoprotein binding

GO:0051220

cytoplasmic sequestering of protein

GO:0051291

protein heterooligomerization