Gene basic information
LiverAtlas Gene ID |
HuLG005167 |
Entrez Gene ID |
|
Official Gene Symbol |
YWHAB |
Synonyms |
GW128|HS1|KCIPN1|YWHAA |
Gene name |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide |
Gene Type |
protein-coding |
Chromosome |
20 |
Genomics Location |
20q13.1 |
Known cancer genes |
Yes |
Protein products |
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide |
Related liver disease name |
|
Database cross reference |
HGNC:12849
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000165 |
MAPKKK cascade |
GO:0000186 |
activation of MAPKK activity |
GO:0003714 |
transcription corepressor activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005730 |
nucleolus |
GO:0005737 |
cytoplasm |
GO:0005813 |
centrosome |
GO:0005829 |
cytosol |
GO:0006605 |
protein targeting |
GO:0006915 |
apoptosis |
GO:0007173 |
epidermal growth factor receptor signaling pathway |
GO:0007264 |
small GTPase mediated signal transduction |
GO:0007265 |
Ras protein signal transduction |
GO:0007411 |
axon guidance |
GO:0008022 |
protein C-terminus binding |
GO:0008286 |
insulin receptor signaling pathway |
GO:0008629 |
induction of apoptosis by intracellular signals |
GO:0008633 |
activation of pro-apoptotic gene products |
GO:0016070 |
RNA metabolic process |
GO:0016071 |
mRNA metabolic process |
GO:0017053 |
transcriptional repressor complex |
GO:0019899 |
enzyme binding |
GO:0019904 |
protein domain specific binding |
GO:0032403 |
protein complex binding |
GO:0035308 |
negative regulation of protein dephosphorylation |
GO:0042470 |
melanosome |
GO:0042826 |
histone deacetylase binding |
GO:0043085 |
positive regulation of catalytic activity |
GO:0048011 |
nerve growth factor receptor signaling pathway |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0050815 |
phosphoserine binding |
GO:0051219 |
phosphoprotein binding |
GO:0051220 |
cytoplasmic sequestering of protein |
GO:0051291 |
protein heterooligomerization |