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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005173

Entrez Gene ID

7536

Official Gene Symbol

SF1

Synonyms

BBP|D11S636|MBBP|ZFM1|ZNF162

Gene name

splicing factor 1

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13

Known cancer genes

Yes

Protein products

cDNA FLJ54737, highly similar to Splicing factor 1

Uncharacterized protein

Splicing factor 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12950
MIM:601516
Ensembl:ENSG00000168066
HPRD:03306
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000245

spliceosome assembly

GO:0000389

nuclear mRNA 3'-splice site recognition

GO:0000398

nuclear mRNA splicing, via spliceosome

GO:0003676

nucleic acid binding

GO:0003714

transcription corepressor activity

GO:0003723

RNA binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005681

spliceosomal complex

GO:0005730

nucleolus

GO:0005840

ribosome

GO:0006355

regulation of transcription, DNA-dependent

GO:0008270

zinc ion binding

GO:0008380

RNA splicing

GO:0022402

cell cycle process

GO:0030238

male sex determination

GO:0033327

Leydig cell differentiation

GO:0046872

metal ion binding

GO:0048662

negative regulation of smooth muscle cell proliferation

GO:0050810

regulation of steroid biosynthetic process