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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005174

Entrez Gene ID

7538

Official Gene Symbol

ZFP36

Synonyms

G0S24|GOS24|NUP475|RNF162A|TIS11|TTP

Gene name

zinc finger protein 36, C3H type, homolog (mouse)

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.1

Known cancer genes

Yes

Protein products

Tristetraprolin

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12862
MIM:190700
Ensembl:ENSG00000128016
HPRD:01835
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003677

DNA binding

GO:0003727

single-stranded RNA binding

GO:0003729

mRNA binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006402

mRNA catabolic process

GO:0007243

intracellular protein kinase cascade

GO:0008270

zinc ion binding

GO:0016070

RNA metabolic process

GO:0016071

mRNA metabolic process

GO:0017091

AU-rich element binding

GO:0043488

regulation of mRNA stability

GO:0045638

negative regulation of myeloid cell differentiation

GO:0046872

metal ion binding

GO:0050728

negative regulation of inflammatory response

GO:0050779

RNA destabilization

GO:0060213

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening