Gene basic information
| LiverAtlas Gene ID |
HuLG005245 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ZBTB16 |
|
Synonyms |
PLZF|ZNF145 |
|
Gene name |
zinc finger and BTB domain containing 16 |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q23.1 |
|
Known cancer genes |
Yes |
|
Protein products |
Promyelocytic leukemia zinc finger Promyelocytic leukemia zinc finger |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:12930
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001823 |
mesonephros development |
|
GO:0003677 |
DNA binding |
|
GO:0003690 |
double-stranded DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005634 |
nucleus |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006915 |
apoptosis |
|
GO:0007417 |
central nervous system development |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0008270 |
zinc ion binding |
|
GO:0016604 |
nuclear body |
|
GO:0016605 |
PML body |
|
GO:0016607 |
nuclear speck |
|
GO:0017053 |
transcriptional repressor complex |
|
GO:0019904 |
protein domain specific binding |
|
GO:0030097 |
hemopoiesis |
|
GO:0030099 |
myeloid cell differentiation |
|
GO:0034504 |
protein localization to nucleus |
|
GO:0035116 |
embryonic hindlimb morphogenesis |
|
GO:0042733 |
embryonic digit morphogenesis |
|
GO:0042802 |
identical protein binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0045638 |
negative regulation of myeloid cell differentiation |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0046872 |
metal ion binding |
