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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005304

Entrez Gene ID

7804

Official Gene Symbol

LRP8

Synonyms

APOER2|HSZ75190|MCI1

Gene name

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p34

Known cancer genes

Yes

Protein products

Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, isoform CRA e

Low-density lipoprotein receptor-related protein 8

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:6700
MIM:602600
Ensembl:ENSG00000157193
HPRD:04002
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

 

Ontology annotation

GO ID

GO annotation

GO:0004888

transmembrane receptor activity

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0005901

caveola

GO:0006508

proteolysis

GO:0006629

lipid metabolic process

GO:0006897

endocytosis

GO:0007165

signal transduction

GO:0007596

blood coagulation

GO:0016021

integral to membrane

GO:0019221

cytokine-mediated signaling pathway

GO:0021766

hippocampus development

GO:0021819

layer formation in cerebral cortex

GO:0030168

platelet activation

GO:0030229

very-low-density lipoprotein particle receptor activity

GO:0034187

apolipoprotein E binding

GO:0045860

positive regulation of protein kinase activity