Gene basic information
| LiverAtlas Gene ID |
HuLG005320 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CXCR4 |
|
Synonyms |
CD184|D2S201E|FB22|HM89|HSY3RR|LAP3|LCR1|LESTR|NPY3R|NPYR|NPYRL|NPYY3R|WHIM |
|
Gene name |
chemokine (C-X-C motif) receptor 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection |
|
Database cross reference |
HGNC:2561
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0001666 |
response to hypoxia |
|
GO:0002407 |
dendritic cell chemotaxis |
|
GO:0003779 |
actin binding |
|
GO:0004930 |
G-protein coupled receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0006915 |
apoptosis |
|
GO:0006954 |
inflammatory response |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007204 |
elevation of cytosolic calcium ion concentration |
|
GO:0009615 |
response to virus |
|
GO:0009986 |
cell surface |
|
GO:0015026 |
coreceptor activity |
|
GO:0016021 |
integral to membrane |
|
GO:0016023 |
cytoplasmic membrane-bounded vesicle |
|
GO:0016032 |
viral reproduction |
|
GO:0016494 |
C-X-C chemokine receptor activity |
|
GO:0019059 |
initiation of viral infection |
|
GO:0030260 |
entry into host cell |
|
GO:0031252 |
cell leading edge |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0031625 |
ubiquitin protein ligase binding |
|
GO:0032027 |
myosin light chain binding |
|
GO:0043130 |
ubiquitin binding |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0050920 |
regulation of chemotaxis |
