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Gene basic information

LiverAtlas Gene ID

HuLG005325

Entrez Gene ID

7867

Official Gene Symbol

MAPKAPK3

Synonyms

3PK|MAPKAP3

Gene name

mitogen-activated protein kinase-activated protein kinase 3

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p21.3

Known cancer genes

Yes

Protein products

MAP kinase-activated protein kinase 3

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Database cross reference

HGNC:6888
MIM:602130
Ensembl:ENSG00000114738
HPRD:03678
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000187

activation of MAPK activity

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0004674

protein serine/threonine kinase activity

GO:0004708

MAP kinase kinase activity

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006950

response to stress

GO:0007165

signal transduction

GO:0007265

Ras protein signal transduction

GO:0008063

Toll signaling pathway

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0045087

innate immune response

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051403

stress-activated MAPK cascade