HuLG005384

Entrez Gene ID

8078

Official Gene Symbol

USP5

Synonyms

ISOT

Gene name

ubiquitin specific peptidase 5 (isopeptidase T)

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p13

Known cancer genes

Yes

Protein products

Ubiquitin carboxyl-terminal hydrolase 5

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12628
MIM:601447
Ensembl:ENSG00000111667
HPRD:03265
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0004197

cysteine-type endopeptidase activity

GO:0004221

ubiquitin thiolesterase activity

GO:0005515

protein binding

GO:0005764

lysosome

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0008233

peptidase activity

GO:0008242

omega peptidase activity

GO:0008270

zinc ion binding

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

GO:0046872

metal ion binding

GO:0071108

protein K48-linked deubiquitination