Gene basic information
| LiverAtlas Gene ID |
HuLG005462 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AXIN1 |
|
Synonyms |
AXIN|MGC52315 |
|
Gene name |
axin 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
16 |
|
Genomics Location |
16p13.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:903
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000209 |
protein polyubiquitination |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001743 |
optic placode formation |
|
GO:0001934 |
positive regulation of protein phosphorylation |
|
GO:0002039 |
p53 binding |
|
GO:0004871 |
signal transducer activity |
|
GO:0005096 |
GTPase activator activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005625 |
soluble fraction |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005881 |
cytoplasmic microtubule |
|
GO:0005886 |
plasma membrane |
|
GO:0005938 |
cell cortex |
|
GO:0006913 |
nucleocytoplasmic transport |
|
GO:0006915 |
apoptosis |
|
GO:0007165 |
signal transduction |
|
GO:0007257 |
activation of JUN kinase activity |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007368 |
determination of left/right symmetry |
|
GO:0007605 |
sensory perception of sound |
|
GO:0008013 |
beta-catenin binding |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0008219 |
cell death |
|
GO:0009950 |
dorsal/ventral axis specification |
|
GO:0010800 |
positive regulation of peptidyl-threonine phosphorylation |
|
GO:0014069 |
postsynaptic density |
|
GO:0016023 |
cytoplasmic membrane-bounded vesicle |
|
GO:0016328 |
lateral plasma membrane |
|
GO:0019899 |
enzyme binding |
|
GO:0019901 |
protein kinase binding |
|
GO:0021797 |
forebrain anterior/posterior pattern formation |
|
GO:0021881 |
Wnt receptor signaling pathway involved in forebrain neuron fate commitment |
|
GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
|
GO:0030511 |
positive regulation of transforming growth factor beta receptor signaling pathway |
|
GO:0030877 |
beta-catenin destruction complex |
|
GO:0030910 |
olfactory placode formation |
|
GO:0031122 |
cytoplasmic microtubule organization |
|
GO:0031398 |
positive regulation of protein ubiquitination |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0031625 |
ubiquitin protein ligase binding |
|
GO:0032147 |
activation of protein kinase activity |
|
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0032947 |
protein complex scaffold |
|
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
|
GO:0034244 |
negative regulation of transcription elongation from RNA polymerase II promoter |
|
GO:0034742 |
APC-Axin-1-beta-catenin complex |
|
GO:0034747 |
Axin-APC-beta-catenin-GSK3B complex |
|
GO:0035121 |
tail morphogenesis |
|
GO:0035412 |
regulation of catenin import into nucleus |
|
GO:0042802 |
identical protein binding |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043547 |
positive regulation of GTPase activity |
|
GO:0043621 |
protein self-association |
|
GO:0043623 |
cellular protein complex assembly |
|
GO:0045599 |
negative regulation of fat cell differentiation |
|
GO:0045732 |
positive regulation of protein catabolic process |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0046332 |
SMAD binding |
|
GO:0048048 |
embryonic eye morphogenesis |
|
GO:0048318 |
axial mesoderm development |
|
GO:0048320 |
axial mesoderm formation |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0051248 |
negative regulation of protein metabolic process |
|
GO:0051260 |
protein homooligomerization |
|
GO:0051443 |
positive regulation of ubiquitin-protein ligase activity |
|
GO:0055001 |
muscle cell development |
|
GO:0060070 |
canonical Wnt receptor signaling pathway |
|
GO:0060272 |
embryonic skeletal joint morphogenesis |
|
GO:0060823 |
canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation |
|
GO:0070016 |
armadillo repeat domain binding |
|
GO:0070411 |
I-SMAD binding |
|
GO:0070412 |
R-SMAD binding |
|
GO:0071407 |
cellular response to organic cyclic compound |
|
GO:0071514 |
genetic imprinting |
|
GO:0071944 |
cell periphery |
|
GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
|
GO:0090244 |
Wnt receptor signaling pathway involved in somitogenesis |
|
GO:2000060 |
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
