HuLG005466

Entrez Gene ID

8317

Official Gene Symbol

CDC7

Synonyms

CDC7L1|HsCDC7|Hsk1|MGC117361|MGC126237|MGC126238|huCDC7

Gene name

cell division cycle 7 homolog (S. cerevisiae)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p22

Known cancer genes

Yes

Protein products

Cell division cycle 7 homolog (S. cerevisiae)

cDNA, FLJ93132, highly similar to Homo sapiens CDC7 cell division cycle 7 (S. cerevisiae) (CDC7), mRNA

Cell division cycle 7-related protein kinase

Cell division cycle 7-like protein 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1745
MIM:603311
Ensembl:ENSG00000097046
HPRD:10345
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000216

M/G1 transition of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0004674

protein serine/threonine kinase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0006260

DNA replication

GO:0006468

protein phosphorylation

GO:0008284

positive regulation of cell proliferation

GO:0016301

kinase activity

GO:0016310

phosphorylation

GO:0033261

regulation of S phase

GO:0046872

metal ion binding

GO:0051301

cell division