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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005549

Entrez Gene ID

8431

Official Gene Symbol

NR0B2

Synonyms

FLJ17090|SHP|SHP1

Gene name

nuclear receptor subfamily 0, group B, member 2

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.1

Known cancer genes

Yes

Protein products

Nuclear receptor SHP

Nuclear receptor subfamily 0 group B member 2

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:7961
MIM:604630
Ensembl:ENSG00000131910
HPRD:05219
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003707

steroid hormone receptor activity

GO:0003714

transcription corepressor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0008203

cholesterol metabolic process

GO:0009749

response to glucose stimulus

GO:0010467

gene expression

GO:0019904

protein domain specific binding

GO:0030521

androgen receptor signaling pathway

GO:0031100

organ regeneration

GO:0032024

positive regulation of insulin secretion

GO:0032403

protein complex binding

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0042803

protein homodimerization activity

GO:0042975

peroxisome proliferator activated receptor binding

GO:0043234

protein complex

GO:0046965

retinoid X receptor binding

GO:0046966

thyroid hormone receptor binding