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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005576

Entrez Gene ID

8467

Official Gene Symbol

SMARCA5

Synonyms

ISWI|SNF2H|WCRF135|hISWI|hSNF2H

Gene name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q31.1-q31.2

Known cancer genes

Yes

Protein products

Putative uncharacterized protein SMARCA5

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11101
MIM:603375
Ensembl:ENSG00000153147
HPRD:04538
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000183

chromatin silencing at rDNA

GO:0000793

condensed chromosome

GO:0003677

DNA binding

GO:0004386

helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005677

chromatin silencing complex

GO:0005730

nucleolus

GO:0006200

ATP catabolic process

GO:0006302

double-strand break repair

GO:0006333

chromatin assembly or disassembly

GO:0006334

nucleosome assembly

GO:0006338

chromatin remodeling

GO:0006352

transcription initiation, DNA-dependent

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0009790

embryo development

GO:0016584

nucleosome positioning

GO:0016589

NURF complex

GO:0016787

hydrolase activity

GO:0016818

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO:0016887

ATPase activity

GO:0031213

RSF complex

GO:0031491

nucleosome binding

GO:0034080

CenH3-containing nucleosome assembly at centromere

GO:0042393

histone binding

GO:0043044

ATP-dependent chromatin remodeling

GO:0043596

nuclear replication fork