Gene basic information
| LiverAtlas Gene ID |
HuLG005650 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PIAS1 |
|
Synonyms |
DDXBP1|GBP|GU/RHNII|MGC141878|MGC141879|ZMIZ3 |
|
Gene name |
protein inhibitor of activated STAT, 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
15 |
|
Genomics Location |
15q |
|
Known cancer genes |
Yes |
|
Protein products |
Protein inhibitor of activated STAT1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2752
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003677 |
DNA binding |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0003714 |
transcription corepressor activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0007259 |
JAK-STAT cascade |
|
GO:0008270 |
zinc ion binding |
|
GO:0016607 |
nuclear speck |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0019789 |
SUMO ligase activity |
|
GO:0019899 |
enzyme binding |
|
GO:0030521 |
androgen receptor signaling pathway |
|
GO:0033235 |
positive regulation of protein sumoylation |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0046872 |
metal ion binding |
|
GO:0050681 |
androgen receptor binding |
|
GO:0060333 |
interferon-gamma-mediated signaling pathway |
|
GO:0060334 |
regulation of interferon-gamma-mediated signaling pathway |
