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Gene basic information

LiverAtlas Gene ID

HuLG005669

Entrez Gene ID

8575

Official Gene Symbol

PRKRA

Synonyms

DYT16|PACT|RAX

Gene name

protein kinase, interferon-inducible double stranded RNA dependent activator

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q31.2

Known cancer genes

Yes

Protein products

Interferon-inducible double stranded RNA-dependent protein kinase activator A

Database cross reference

HGNC:9438
MIM:603424
Ensembl:ENSG00000180228
HPRD:04573
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

 

Ontology annotation

GO ID

GO annotation

GO:0003725

double-stranded RNA binding

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0006468

protein phosphorylation

GO:0006917

induction of apoptosis

GO:0006950

response to stress

GO:0006955

immune response

GO:0008047

enzyme activator activity

GO:0008285

negative regulation of cell proliferation

GO:0009615

response to virus

GO:0030422

production of siRNA involved in RNA interference

GO:0031047

gene silencing by RNA

GO:0042473

outer ear morphogenesis

GO:0042474

middle ear morphogenesis

GO:0042803

protein homodimerization activity

GO:0043085

positive regulation of catalytic activity

GO:0048471

perinuclear region of cytoplasm

GO:0048705

skeletal system morphogenesis