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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005711

Entrez Gene ID

8644

Official Gene Symbol

AKR1C3

Synonyms

DD3|DDX|HA1753|HAKRB|HAKRe|HSD17B5|KIAA0119|PGFS|hluPGFS

Gene name

aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)

Gene Type

protein-coding

Chromosome

10

Genomics Location

10p15-p14

Known cancer genes

Yes

Protein products

Aldo-keto reductase family 1 member C3

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:386
MIM:603966
Ensembl:ENSG00000196139
HPRD:04911
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004033

aldo-keto reductase (NADP) activity

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0006693

prostaglandin metabolic process

GO:0016491

oxidoreductase activity

GO:0047017

prostaglandin-F synthase activity

GO:0047026

androsterone dehydrogenase (A-specific) activity

GO:0047045

testosterone 17-beta-dehydrogenase (NADP+) activity

GO:0047115

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

GO:0047718

indanol dehydrogenase activity

GO:0050327

testosterone 17-beta-dehydrogenase (NAD+) activity

GO:0055114

oxidation-reduction process