Gene basic information
LiverAtlas Gene ID |
HuLG005714 |
Entrez Gene ID |
|
Official Gene Symbol |
ABCB11 |
Synonyms |
ABC16|BRIC2|BSEP|PFICN2|PFIC2|PGY4|SPGP |
Gene name |
ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
Gene Type |
protein-coding |
Chromosome |
2 |
Genomics Location |
2q24 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis |
Database cross reference |
HGNC:42
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000139 |
Golgi membrane |
GO:0000166 |
nucleotide binding |
GO:0005215 |
transporter activity |
GO:0005524 |
ATP binding |
GO:0005624 |
membrane fraction |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0006699 |
bile acid biosynthetic process |
GO:0006810 |
transport |
GO:0008206 |
bile acid metabolic process |
GO:0008554 |
sodium-exporting ATPase activity, phosphorylative mechanism |
GO:0015126 |
canalicular bile acid transmembrane transporter activity |
GO:0015432 |
bile acid-exporting ATPase activity |
GO:0015721 |
bile acid and bile salt transport |
GO:0015722 |
canalicular bile acid transport |
GO:0016021 |
integral to membrane |
GO:0016324 |
apical plasma membrane |
GO:0016887 |
ATPase activity |
GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
GO:0046581 |
intercellular canaliculus |
GO:0055085 |
transmembrane transport |