Gene basic information
LiverAtlas Gene ID |
HuLG005720 |
Entrez Gene ID |
|
Official Gene Symbol |
PDE5A |
Synonyms |
CGBNPDE|CN5A|PDE5 |
Gene name |
phosphodiesterase 5A, cGMP-specific |
Gene Type |
protein-coding |
Chromosome |
4 |
Genomics Location |
4q27 |
Protein products |
cGMP-specific 3',5'-cyclic phosphodiesterase Putative uncharacterized protein PDE5A CGMP-specific phosphodiesterase PDE5A2 |
Related liver disease name |
|
Database cross reference |
HGNC:8784
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0001666 |
response to hypoxia |
GO:0002026 |
regulation of the force of heart contraction |
GO:0002678 |
positive regulation of chronic inflammatory response |
GO:0004114 |
3',5'-cyclic-nucleotide phosphodiesterase activity |
GO:0005575 |
cellular component |
GO:0005829 |
cytosol |
GO:0007165 |
signal transduction |
GO:0007399 |
nervous system development |
GO:0007596 |
blood coagulation |
GO:0007614 |
short-term memory |
GO:0008270 |
zinc ion binding |
GO:0009187 |
cyclic nucleotide metabolic process |
GO:0010613 |
positive regulation of cardiac muscle hypertrophy |
GO:0016787 |
hydrolase activity |
GO:0030168 |
platelet activation |
GO:0030553 |
cGMP binding |
GO:0032496 |
response to lipopolysaccharide |
GO:0033574 |
response to testosterone stimulus |
GO:0042130 |
negative regulation of T cell proliferation |
GO:0042311 |
vasodilation |
GO:0043065 |
positive regulation of apoptosis |
GO:0043406 |
positive regulation of MAP kinase activity |
GO:0045907 |
positive regulation of vasoconstriction |
GO:0046069 |
cGMP catabolic process |
GO:0046872 |
metal ion binding |
GO:0047555 |
3',5'-cyclic-GMP phosphodiesterase activity |
GO:0055119 |
relaxation of cardiac muscle |
GO:0060282 |
positive regulation of oocyte development |