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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005765

Entrez Gene ID

8714

Official Gene Symbol

ABCC3

Synonyms

ABC31|DKFZp686E22157|EST90757|MLP2|MOATND|MRP3|cMOAT2

Gene name

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q22

Known cancer genes

Yes

Protein products

Canalicular multispecific organic anion transporter 2

ABCC3 protein

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Primary biliary cirrhosis

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:54
MIM:604323
Ensembl:ENSG00000108846
HPRD:06826
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0005215

transporter activity

GO:0005524

ATP binding

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006810

transport

GO:0008206

bile acid metabolic process

GO:0008514

organic anion transmembrane transporter activity

GO:0015432

bile acid-exporting ATPase activity

GO:0015711

organic anion transport

GO:0015721

bile acid and bile salt transport

GO:0016887

ATPase activity

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO:0055085

transmembrane transport