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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005785

Entrez Gene ID

8738

Official Gene Symbol

CRADD

Synonyms

MGC9163|RAIDD

Gene name

CASP2 and RIPK1 domain containing adaptor with death domain

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q21.33-q23.1

Known cancer genes

Yes

Protein products

CASP2 and RIPK1 domain containing adaptor with death domain

Death domain-containing protein CRADD

CASP2 and RIPK1 domain containing adaptor with death domain

CRADD protein

AID

AID

AID

AID

AID

AID

AID

Truncated AID

AID

AID

AID

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:2340
MIM:603454
Ensembl:ENSG00000169372
HPRD:04584
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002020

protease binding

GO:0005515

protein binding

GO:0005622

intracellular

GO:0006917

induction of apoptosis

GO:0007165

signal transduction

GO:0008625

induction of apoptosis via death domain receptors

GO:0030674

protein binding, bridging

GO:0042981

regulation of apoptosis

GO:0070513

death domain binding

GO:0071260

cellular response to mechanical stimulus