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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005787

Entrez Gene ID

8740

Official Gene Symbol

TNFSF14

Synonyms

CD258|HVEML|LIGHT|LTg|TR2

Gene name

tumor necrosis factor (ligand) superfamily, member 14

Gene Type

protein-coding

Chromosome

19

Genomics Location

19p13.3

Protein products

Tumor necrosis factor ligand superfamily member 14

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:11930
MIM:604520
Ensembl:ENSG00000125735
HPRD:05157
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005102

receptor binding

GO:0005125

cytokine activity

GO:0005164

tumor necrosis factor receptor binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006917

induction of apoptosis

GO:0006955

immune response

GO:0007165

signal transduction

GO:0008588

release of cytoplasmic sequestered NF-kappaB

GO:0016021

integral to membrane

GO:0031295

T cell costimulation

GO:0042098

T cell proliferation

GO:0042110

T cell activation

GO:0043027

caspase inhibitor activity

GO:0043029

T cell homeostasis

GO:0043154

negative regulation of caspase activity

GO:0071260

cellular response to mechanical stimulus