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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005789

Entrez Gene ID

8742

Official Gene Symbol

TNFSF12

Synonyms

APO3L|DR3LG|MGC129581|MGC20669|TWEAK

Gene name

tumor necrosis factor (ligand) superfamily, member 12

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13

Known cancer genes

Yes

Protein products

HCG1991317, isoform CRA b

Tumor necrosis factor ligand superfamily member 12

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11927
MIM:602695
Ensembl:ENSG00000239697
HPRD:04074
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001938

positive regulation of endothelial cell proliferation

GO:0005102

receptor binding

GO:0005125

cytokine activity

GO:0005164

tumor necrosis factor receptor binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006915

apoptosis

GO:0006917

induction of apoptosis

GO:0006955

immune response

GO:0007165

signal transduction

GO:0007275

multicellular organismal development

GO:0030154

cell differentiation

GO:0043542

endothelial cell migration

GO:0045766

positive regulation of angiogenesis

GO:0048471

perinuclear region of cytoplasm