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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005797

Entrez Gene ID

8754

Official Gene Symbol

ADAM9

Synonyms

CORD9|KIAA0021|MCMP|MDC9|Mltng

Gene name

ADAM metallopeptidase domain 9

Gene Type

protein-coding

Chromosome

8

Genomics Location

8p11.22

Known cancer genes

Yes

Protein products

Disintegrin and metalloproteinase domain-containing protein 9

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:216
MIM:602713
Ensembl:ENSG00000168615
HPRD:04091
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000186

activation of MAPKK activity

GO:0004222

metalloendopeptidase activity

GO:0005080

protein kinase C binding

GO:0005178

integrin binding

GO:0005515

protein binding

GO:0005518

collagen binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006508

proteolysis

GO:0006509

membrane protein ectodomain proteolysis

GO:0007155

cell adhesion

GO:0007160

cell-matrix adhesion

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0007229

integrin-mediated signaling pathway

GO:0007601

visual perception

GO:0008233

peptidase activity

GO:0008237

metallopeptidase activity

GO:0008270

zinc ion binding

GO:0009986

cell surface

GO:0010042

response to manganese ion

GO:0016021

integral to membrane

GO:0017124

SH3 domain binding

GO:0030216

keratinocyte differentiation

GO:0031233

intrinsic to external side of plasma membrane

GO:0033627

cell adhesion mediated by integrin

GO:0033630

positive regulation of cell adhesion mediated by integrin

GO:0033631

cell-cell adhesion mediated by integrin

GO:0034241

positive regulation of macrophage fusion

GO:0034612

response to tumor necrosis factor

GO:0042117

monocyte activation

GO:0042542

response to hydrogen peroxide

GO:0043236

laminin binding

GO:0046872

metal ion binding

GO:0050714

positive regulation of protein secretion

GO:0050896

response to stimulus

GO:0051044

positive regulation of membrane protein ectodomain proteolysis

GO:0051088

PMA-inducible membrane protein ectodomain proteolysis

GO:0051384

response to glucocorticoid stimulus

GO:0051549

positive regulation of keratinocyte migration

GO:0051592

response to calcium ion