Gene basic information
| LiverAtlas Gene ID |
HuLG005804 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
RIPK2 |
|
Synonyms |
CARD3|CARDIAK|CCK|GIG30|RICK|RIP2 |
|
Gene name |
receptor-interacting serine-threonine kinase 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8q21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Database cross reference |
HGNC:10020
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0001961 |
positive regulation of cytokine-mediated signaling pathway |
|
GO:0002224 |
toll-like receptor signaling pathway |
|
GO:0002755 |
MyD88-dependent toll-like receptor signaling pathway |
|
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
|
GO:0002827 |
positive regulation of T-helper 1 type immune response |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006916 |
anti-apoptosis |
|
GO:0006954 |
inflammatory response |
|
GO:0007165 |
signal transduction |
|
GO:0007254 |
JNK cascade |
|
GO:0008063 |
Toll signaling pathway |
|
GO:0030274 |
LIM domain binding |
|
GO:0031398 |
positive regulation of protein ubiquitination |
|
GO:0031663 |
lipopolysaccharide-mediated signaling pathway |
|
GO:0032722 |
positive regulation of chemokine production |
|
GO:0032729 |
positive regulation of interferon-gamma production |
|
GO:0032743 |
positive regulation of interleukin-2 production |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032760 |
positive regulation of tumor necrosis factor production |
|
GO:0032874 |
positive regulation of stress-activated MAPK cascade |
|
GO:0033091 |
positive regulation of immature T cell proliferation |
|
GO:0034130 |
toll-like receptor 1 signaling pathway |
|
GO:0034134 |
toll-like receptor 2 signaling pathway |
|
GO:0034138 |
toll-like receptor 3 signaling pathway |
|
GO:0034142 |
toll-like receptor 4 signaling pathway |
|
GO:0042098 |
T cell proliferation |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043330 |
response to exogenous dsRNA |
|
GO:0045087 |
innate immune response |
|
GO:0045627 |
positive regulation of T-helper 1 cell differentiation |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0046641 |
positive regulation of alpha-beta T cell proliferation |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0050700 |
CARD domain binding |
|
GO:0050830 |
defense response to Gram-positive bacterium |
|
GO:0050852 |
T cell receptor signaling pathway |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051403 |
stress-activated MAPK cascade |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
|
GO:0070427 |
nucleotide-binding oligomerization domain containing 1 signaling pathway |
|
GO:0070431 |
nucleotide-binding oligomerization domain containing 2 signaling pathway |
|
GO:0070555 |
response to interleukin-1 |
|
GO:0070671 |
response to interleukin-12 |
|
GO:0070673 |
response to interleukin-18 |
|
GO:0071223 |
cellular response to lipoteichoic acid |
|
GO:0071224 |
cellular response to peptidoglycan |
