Gene basic information
| LiverAtlas Gene ID |
HuLG005806 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
FADD |
|
Synonyms |
MGC8528|MORT1 |
|
Gene name |
Fas (TNFRSF6)-associated via death domain |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q13.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3573
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005123 |
death receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0007165 |
signal transduction |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0008625 |
induction of apoptosis via death domain receptors |
|
GO:0008633 |
activation of pro-apoptotic gene products |
|
GO:0031264 |
death-inducing signaling complex |
|
GO:0031265 |
CD95 death-inducing signaling complex |
|
GO:0032757 |
positive regulation of interleukin-8 production |
|
GO:0032760 |
positive regulation of tumor necrosis factor production |
|
GO:0032813 |
tumor necrosis factor receptor superfamily binding |
|
GO:0042802 |
identical protein binding |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0043005 |
neuron projection |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0044297 |
cell body |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045087 |
innate immune response |
|
GO:0045121 |
membrane raft |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0051291 |
protein heterooligomerization |
|
GO:0051607 |
defense response to virus |
|
GO:0060340 |
positive regulation of type I interferon-mediated signaling pathway |
|
GO:0070265 |
necrotic cell death |
|
GO:0071260 |
cellular response to mechanical stimulus |
