HuLG005821

Entrez Gene ID

8792

Official Gene Symbol

TNFRSF11A

Synonyms

CD265|FEO|LOH18CR1|ODFR|OFE|OPTB7|OSTS|PDB2|RANK|TRANCER

Gene name

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Gene Type

protein-coding

Chromosome

18

Genomics Location

18q22.1

Known cancer genes

Yes

Protein products

Tumor necrosis factor receptor superfamily member 11A

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:11908
MIM:603499
Ensembl:ENSG00000141655
HPRD:04609
RefSeq Genomic nucleotide accession:AC_000061
RefSeq Genomic nucleotide gi:89161196

GO annotation

GO:0001503

ossification

GO:0002250

adaptive immune response

GO:0002548

monocyte chemotaxis

GO:0004872

receptor activity

GO:0004888

transmembrane receptor activity

GO:0005031

tumor necrosis factor receptor activity

GO:0005515

protein binding

GO:0007165

signal transduction

GO:0007267

cell-cell signaling

GO:0007275

multicellular organismal development

GO:0008284

positive regulation of cell proliferation

GO:0009897

external side of plasma membrane

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0019955

cytokine binding

GO:0030316

osteoclast differentiation

GO:0032496

response to lipopolysaccharide

GO:0033209

tumor necrosis factor-mediated signaling pathway

GO:0034097

response to cytokine stimulus

GO:0034612

response to tumor necrosis factor

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043507

positive regulation of JUN kinase activity

GO:0046872

metal ion binding

GO:0048535

lymph node development

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO:0060086

circadian temperature homeostasis

GO:0060749

mammary gland alveolus development

GO:0070555

response to interleukin-1

GO:0071812

positive regulation of fever generation by positive regulation of prostaglandin secretion

GO:0071847

TNFSF11-mediated signaling pathway

GO:0071848

positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling