Gene basic information
| LiverAtlas Gene ID |
HuLG005826 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TNFRSF10A |
|
Synonyms |
APO2|CD261|DR4|MGC9365|TRAILRN1|TRAILR1 |
|
Gene name |
tumor necrosis factor receptor superfamily, member 10a |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8p21 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11904
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004872 |
receptor activity |
|
GO:0005035 |
death receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0007165 |
signal transduction |
|
GO:0007250 |
activation of NF-kappaB-inducing kinase activity |
|
GO:0008134 |
transcription factor binding |
|
GO:0008625 |
induction of apoptosis via death domain receptors |
|
GO:0008656 |
caspase activator activity |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0045569 |
TRAIL binding |
|
GO:0071260 |
cellular response to mechanical stimulus |
