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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005853

Entrez Gene ID

8826

Official Gene Symbol

IQGAP1

Synonyms

HUMORFA01|KIAA0051|SAR1|p195

Gene name

IQ motif containing GTPase activating protein 1

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q26.1

Known cancer genes

Yes

Protein products

IQ motif containing GTPase activating protein 1

Ras GTPase-activating-like protein IQGAP1

IQGAP1 protein

IQGAP1 protein

IQGAP1 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:6110
MIM:603379
Ensembl:ENSG00000140575
HPRD:04541
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005095

GTPase inhibitor activity

GO:0005096

GTPase activator activity

GO:0005099

Ras GTPase activator activity

GO:0005515

protein binding

GO:0005516

calmodulin binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005884

actin filament

GO:0005886

plasma membrane

GO:0006112

energy reserve metabolic process

GO:0007165

signal transduction

GO:0016020

membrane

GO:0019903

protein phosphatase binding

GO:0030496

midbody

GO:0032403

protein complex binding

GO:0043547

positive regulation of GTPase activity

GO:0050796

regulation of insulin secretion

GO:0051056

regulation of small GTPase mediated signal transduction