Gene basic information
| LiverAtlas Gene ID |
HuLG005860 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SOCS2 |
|
Synonyms |
CIS2|Cish2|SOCSN2|SSIN2|SSI2|STATI2 |
|
Gene name |
suppressor of cytokine signaling 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q |
|
Known cancer genes |
Yes |
|
Protein products |
Suppressor of cytokine signaling 2, isoform CRA a |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:19382
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001558 |
regulation of cell growth |
|
GO:0005070 |
SH3/SH2 adaptor activity |
|
GO:0005131 |
growth hormone receptor binding |
|
GO:0005148 |
prolactin receptor binding |
|
GO:0005159 |
insulin-like growth factor receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0006916 |
anti-apoptosis |
|
GO:0007259 |
JAK-STAT cascade |
|
GO:0007568 |
aging |
|
GO:0008269 |
JAK pathway signal transduction adaptor activity |
|
GO:0009966 |
regulation of signal transduction |
|
GO:0009968 |
negative regulation of signal transduction |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032870 |
cellular response to hormone stimulus |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0043434 |
response to peptide hormone stimulus |
|
GO:0060396 |
growth hormone receptor signaling pathway |
