HuLG005957

Entrez Gene ID

8986

Official Gene Symbol

RPS6KA4

Synonyms

MSK2|RSKNB

Gene name

ribosomal protein S6 kinase, 90kDa, polypeptide 4

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q11-q13

Known cancer genes

Yes

Protein products

RPS6KA4 protein

Ribosomal protein S6 kinase alpha-4

Database cross reference

HGNC:10433
MIM:603606
Ensembl:ENSG00000162302
HPRD:04677
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

GO annotation

GO:0000166

nucleotide binding

GO:0000287

magnesium ion binding

GO:0004674

protein serine/threonine kinase activity

GO:0004711

ribosomal protein S6 kinase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0006468

protein phosphorylation

GO:0007243

intracellular protein kinase cascade

GO:0007411

axon guidance

GO:0016572

histone phosphorylation

GO:0033129

positive regulation of histone phosphorylation

GO:0035066

positive regulation of histone acetylation

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048273

mitogen-activated protein kinase p38 binding

GO:0070498

interleukin-1-mediated signaling pathway