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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG005977

Entrez Gene ID

9021

Official Gene Symbol

SOCS3

Synonyms

ATOD4|CIS3|Cish3|MGC71791|SOCSN3|SSIN3|SSI3

Gene name

suppressor of cytokine signaling 3

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q25.3

Known cancer genes

Yes

Protein products

SOCS3 protein

Suppressor of cytokine signaling 3

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:19391
MIM:604176
Ensembl:ENSG00000184557
HPRD:05006
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0001932

regulation of protein phosphorylation

GO:0004860

protein kinase inhibitor activity

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006916

anti-apoptosis

GO:0007259

JAK-STAT cascade

GO:0007568

aging

GO:0009408

response to heat

GO:0009617

response to bacterium

GO:0010332

response to gamma radiation

GO:0014070

response to organic cyclic compound

GO:0019221

cytokine-mediated signaling pathway

GO:0031100

organ regeneration

GO:0032094

response to food

GO:0032355

response to estradiol stimulus

GO:0032496

response to lipopolysaccharide

GO:0032570

response to progesterone stimulus

GO:0032868

response to insulin stimulus

GO:0034097

response to cytokine stimulus

GO:0040008

regulation of growth

GO:0042493

response to drug

GO:0045597

positive regulation of cell differentiation

GO:0046627

negative regulation of insulin receptor signaling pathway

GO:0051384

response to glucocorticoid stimulus

GO:0060333

interferon-gamma-mediated signaling pathway

GO:0060334

regulation of interferon-gamma-mediated signaling pathway

GO:0060337

type I interferon-mediated signaling pathway

GO:0060338

regulation of type I interferon-mediated signaling pathway

GO:0060670

branching involved in embryonic placenta morphogenesis

GO:0060674

placenta blood vessel development

GO:0060707

trophoblast giant cell differentiation

GO:0060708

spongiotrophoblast differentiation