HuLG005991

Entrez Gene ID

9039

Official Gene Symbol

UBA3

Synonyms

DKFZp566J164|MGC22384|UBE1C|hUBA3

Gene name

ubiquitin-like modifier activating enzyme 3

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p24.3-p13

Known cancer genes

Yes

Protein products

NEDD8-activating enzyme E1 catalytic subunit

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:12470
MIM:603172
Ensembl:ENSG00000144744
HPRD:04413
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000166

nucleotide binding

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0006464

protein modification process

GO:0006508

proteolysis

GO:0007113

endomitotic cell cycle

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0016922

ligand-dependent nuclear receptor binding

GO:0019781

NEDD8 activating enzyme activity

GO:0045116

protein neddylation

GO:0046982

protein heterodimerization activity

GO:0051726

regulation of cell cycle