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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006060

Entrez Gene ID

9126

Official Gene Symbol

SMC3

Synonyms

BAM|BMH|CDLS3|CSPG6|HCAP|SMC3L1

Gene name

structural maintenance of chromosomes 3

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q25

Known cancer genes

Yes

Protein products

Structural maintenance of chromosomes 3

Structural maintenance of chromosomes protein 3

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:2468
MIM:606062
Ensembl:ENSG00000108055
HPRD:05829
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000087

M phase of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000236

mitotic prometaphase

GO:0000278

mitotic cell cycle

GO:0000775

chromosome, centromeric region

GO:0000785

chromatin

GO:0000800

lateral element

GO:0000922

spindle pole

GO:0003777

microtubule motor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005604

basement membrane

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005694

chromosome

GO:0005737

cytoplasm

GO:0006275

regulation of DNA replication

GO:0006281

DNA repair

GO:0007052

mitotic spindle organization

GO:0007062

sister chromatid cohesion

GO:0007067

mitosis

GO:0007091

mitotic metaphase/anaphase transition

GO:0007126

meiosis

GO:0007165

signal transduction

GO:0008278

cohesin complex

GO:0009294

DNA mediated transformation

GO:0016363

nuclear matrix

GO:0030893

meiotic cohesin complex

GO:0032876

negative regulation of DNA endoreduplication

GO:0045502

dynein binding

GO:0046982

protein heterodimerization activity

GO:0051301

cell division