Gene basic information
| LiverAtlas Gene ID |
HuLG006065 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
AIFM1 |
|
Synonyms |
AIF|COXPD6|MGC111425|PDCD8 |
|
Gene name |
apoptosis-inducing factor, mitochondrion-associated, 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
0 |
|
Genomics Location |
Xq26.1 |
|
Known cancer genes |
Yes |
|
Protein products |
Apoptosis-inducing factor 1, mitochondrial Apoptosis-inducing factor short isoform 3 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8768
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003677 |
DNA binding |
|
GO:0005515 |
protein binding |
|
GO:0005625 |
soluble fraction |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005743 |
mitochondrial inner membrane |
|
GO:0005758 |
mitochondrial intermembrane space |
|
GO:0005792 |
microsome |
|
GO:0005829 |
cytosol |
|
GO:0006309 |
DNA fragmentation involved in apoptotic nuclear change |
|
GO:0006919 |
activation of caspase activity |
|
GO:0008630 |
DNA damage response, signal transduction resulting in induction of apoptosis |
|
GO:0009055 |
electron carrier activity |
|
GO:0016020 |
membrane |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0045454 |
cell redox homeostasis |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0050660 |
flavin adenine dinucleotide binding |
|
GO:0051402 |
neuron apoptosis |
|
GO:0070059 |
apoptosis in response to endoplasmic reticulum stress |
