Gene basic information
| LiverAtlas Gene ID |
HuLG006071 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ARHGEF1 |
|
Synonyms |
GEF1|LBCL2|LSC|P115NRHOGEF|SUB1.5 |
|
Gene name |
Rho guanine nucleotide exchange factor (GEF) 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
19 |
|
Genomics Location |
19q13.13 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:681
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
GO:0005096 |
GTPase activator activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0007266 |
Rho protein signal transduction |
|
GO:0008283 |
cell proliferation |
|
GO:0035023 |
regulation of Rho protein signal transduction |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0050770 |
regulation of axonogenesis |
|
GO:0050771 |
negative regulation of axonogenesis |
|
GO:0050772 |
positive regulation of axonogenesis |
