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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006122

Entrez Gene ID

9212

Official Gene Symbol

AURKB

Synonyms

AIK2|AIMN1|AIM1|ARK2|AurB|IPL1|STK12|STK5|aurkbNsv1|aurkbNsv2

Gene name

aurora kinase B

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13.1

Known cancer genes

Yes

Protein products

Serine/threonine-protein kinase 12

Aurora kinase B

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:11390
MIM:604970
Ensembl:ENSG00000178999
HPRD:05397
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000087

M phase of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000236

mitotic prometaphase

GO:0000278

mitotic cell cycle

GO:0000779

condensed chromosome, centromeric region

GO:0000780

condensed nuclear chromosome, centromeric region

GO:0000910

cytokinesis

GO:0004674

protein serine/threonine kinase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005694

chromosome

GO:0005737

cytoplasm

GO:0005819

spindle

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0006468

protein phosphorylation

GO:0007568

aging

GO:0008283

cell proliferation

GO:0030496

midbody

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0032133

chromosome passenger complex

GO:0034501

protein localization to kinetochore

GO:0046872

metal ion binding