HuLG006262

Entrez Gene ID

9414

Official Gene Symbol

TJP2

Synonyms

MGC26306|X104|ZO2

Gene name

tight junction protein 2 (zona occludens 2)

Gene Type

protein-coding

Chromosome

9

Genomics Location

9q13-q21

Known cancer genes

Yes

Protein products

Tight junction protein 2 (Zona occludens 2)

cDNA FLJ59510, highly similar to Homo sapiens tight junction protein 2 (TJP2), transcript variant 2, mRNA

cDNA FLJ53324, highly similar to Tight junction protein ZO-2

cDNA FLJ54712, highly similar to Tight junction protein ZO-2

cDNA FLJ61560, highly similar to Tight junction protein ZO-2

Tight junction protein ZO-2

Related liver disease name

Hepatocellular carcinoma

Primary sclerosing cholangitis

Database cross reference

HGNC:11828
MIM:607709
Ensembl:ENSG00000119139
HPRD:06369
RefSeq Genomic nucleotide accession:AC_000052
RefSeq Genomic nucleotide gi:89161215

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

GO annotation

GO:0004385

guanylate kinase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005912

adherens junction

GO:0005923

tight junction

GO:0006915

apoptosis

GO:0006921

cellular component disassembly involved in apoptosis

GO:0030054

cell junction