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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG006274

Entrez Gene ID

9429

Official Gene Symbol

ABCG2

Synonyms

ABC15|ABCP|BCRP|BCRP1|BMDP|CD338|CDw338|EST157481|MGC102821|MRX|MXR|MXR1

Gene name

ATP-binding cassette, sub-family G (WHITE), member 2

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q22

Known cancer genes

Yes

Protein products

ATP-binding cassette sub-family G member 2

Putative uncharacterized protein ABCG2

Breast cancer resistance protein

Related liver disease name

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:74
MIM:603756
Ensembl:ENSG00000118777
HPRD:04783
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0005215

transporter activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0006810

transport

GO:0006879

cellular iron ion homeostasis

GO:0008559

xenobiotic-transporting ATPase activity

GO:0015232

heme transporter activity

GO:0015886

heme transport

GO:0016021

integral to membrane

GO:0016887

ATPase activity

GO:0042493

response to drug

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

GO:0042803

protein homodimerization activity

GO:0046415

urate metabolic process

GO:0055085

transmembrane transport